产品货号:
Z35738
中文名称:
NTAL/LAT2 Purified抗体
英文名称:
Anti-NTAL/LAT2 Purified Antibody (Clone#NAP-03)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NTAL/LAT2 Purified Antibody (Clone#NAP-03) |
指标别名 | LAT2;LAB;NTAL;WBS15;WBSCR15;WBSCR5;HSPC046;Linker for activation of T-cells family member 2;Linker for activation of B-cells;Membrane-associated adapter molecule;Non-T-cell activation linker;Williams-Beuren syndrome chromosomal region 15 protein;Williams-Beuren syndrome chromosomal region 5 protein |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | IP,WB,IHC |
基因名称 | LAT2 |
克隆号 | NAP-03 |
抗体来源 | Mouse |
抗体类型 | IgG2a |
免疫原 | Peptide corresponding to aa 196-212 of human NTAL coupled to KLH.The antibody NAP-03 recognizes a defined intracellular epitope (aa 196-212) of human Non-T cell Activation Linker (NTAL),also known as LAB (linker of activated B cells),a 30kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B cells,NK cells and myeloid cells. |
计算分子量 | 27kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | NTAL (non-T cell activation linker),also known as LAB (linker for activation of B cells),is a 30kDa double-palmitoylated transmembrane adaptor protein expressed by B cells,NK cells,mast cells and macrophages.It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells.However,in mast cells,NTAL also contributes to some activation processes,partially overlapping with LAT function. |
Uniprot ID | Q9GZY6 |
基因名全称 | Linker for activation of T cells family member 2 |
蛋白名全称 | Linker for activation of T-cells family member 2 |
推荐稀释比 | Immunohistochemistry (paraffin sections):5μg/mL;positive tissue:tonsil,germinal center. Western blotting:1~2μg/mL,incubation 60min;positive control:RAMOS human lymphoma cell line;non-reducing conditions,12% separating SDS-PAGE gel. |
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